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Piroxicam (Feldene)NSAIDs

INDICATION

A nonsteroidal anti-inflammatory and painkiller used to treat arthritis.

SIDE EFFECTS

GI bleeding, ulcers, gastritis, nausea, abdominal pain, anorexia, anaemia, itching, rash, dizziness, ringing in the ears, increased bleeding time, headache, swelling, kidney dysfunction, elevated liver enzymes, and photosensitivity.

INTERACTIONS and PRECAUTIONS

  1. Anticoagulants (Warfarin) can increase bleeding if taken concurrently.
  2. Lithium may have INCREASED levels.
  3. Use with ACE inhibitors (captopril, lisinopril, enalapril) decrease the ACE inhibitor effect.
  4. Use with diuretics can decrease the diuretic effect.
  5. Use with aspirin, cortisone medications, or alcohol can promote the risk of stomach ulcers and bleeding.
  6. Use with beta-blockers (propranolol, metoprolol, nadolol, labetalol, carteolol) can decrease the antihypertensive effect.

USUAL DOSE

Adults: oral, 20 mg once a day or 10 mg twice a day.

Paediatrics: dosage not established.

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