Anti-inflammatory agent used in both the treatment of osteoarthritis and pain management.
Chills, fever, indigestion, abdominal pain, diarrhoea, nausea, constipation, blood in stools (black stools), vomiting, dizziness, nervousness, rash, itching, blurred vision, ringing in the ears, hypertension, palpitations, dry mouth, thirst, loss of appetite, elevated liver enzymes, bruising, anaemia, asthma, and allergic reactions (in those sensitive to aspirin or nonsteroidal anti-inflammatory agents).
Concomitant use with aspirin can increase the potential for drug side effects.
Cyclosporin, digoxin, lithium, and methotrexate can result in higher blood levels, leading to toxicity.
USUAL DOSE
Adults: oral, 200-400 mg every six to eight hours as needed for pain.