(BRITISH) UK Trade name products: (Sandimmun)
This is an immunosuppresive agent used to prevent organ rejection in kidney, liver, bone marrow, or heart transplant patients.
Common side effects are: inflammation of the gums, blood in the urine, jaundice, tremors, and increased hair growth. Other less common effects include: headache, hypertension, hyperplasia (enlargement) of the gums, nausea, vomiting, diarrhoea, oral thrush, fever, sore throat, leg cramps, kidney toxicity, liver toxicity, acne, sinusitis, and flushing. Rare side effects include: confusion, irregular heart beat, abdominal pain, and weakness.
For transplant rejection prevention: oral, 12-15 mg/kg body weight per day (initially), beginning four to twelve hours before surgery and continuing for 2 weeks after surgery. Maintenance dosing of 5-10 mg/kg body weight per day.