N.A.S.S Dingwall Branch Information Page

Aspirin

(BRITISH) UK Trade name products: (Anadin) (Aspro) (Bayer) (Beechams powders) (Caprin) (Disprin) (Nu-seals Aspirin) (Phensic) (Toptabs)

(AMERICAN) US Trade name products which contain aspirin as the key ingredient include: (217) (217 Strong) (8-Hour Bayer Timed-Release) (Anacin) (Apac Improved) (Apo-Asa) (Apo-Asen) (Arthrinol Aspirin Tablets) (Arthrisin) (Atria S.R.) (Aspergum) (Astrin) (Bayer Aspirin) (Bayer Timed-Release Arthritic Pain Formula) (C2) (Coryphen) (Easprin) (Ecotrin) (Empirin) (Entrophen) (Halfprin) (Headstart) (Instantine) (Measurin) (Nervine) (Norwich Aspirin) (Novasen) (P-A-C Revised Formula) (Riphen) (Sal-Adult) (Sal-Infant) (St. Joseph Adult Chewable Aspirin) (Supasa) (Therapy Bayer) (Triaphen Aspirin Dispersible Tablets) (Zorprin)

INDICATION

A salicylate medication used to relieve mild pain, reduce fever, thin the blood, and as an anti-inflammatory agent.

SIDE EFFECTS

Prolonged bleeding time, wheezing, ringing in the ears, nausea, vomiting, GI upset, GI bleeding, ulcers, rash, allergic reactions, hives, bruising, abnormal liver function tests, and hepatitis.

INTERACTIONS and PRECAUTIONS

  1. Blood thinners (Warfarin, heparin) can increase the risk of bleeding.
  2. Monitor closely when taken with cortisone medications (can increase stomach ulcers).
  3. Antacids can decrease aspirin levels.
  4. Use with beta-blockers (acebutolol) can lead to decreased antihypertensive effect of acebutolol.
  5. Use with ACE inhibitors (captopril, Zestril, enalapril) can lead to decreased ACE inhibitor effect.
  6. Use with allopurinol can lead to decreased allopurinol effect.
  7. Use with antacids can lead to decreased aspirin effect.
  8. Use with bumetanide, ethacrynic acid, or frusemide (frusemide) can lead to possible aspirin toxicity.
  9. Use with diclofenac can lead to increased risk of stomach ulcer.
  10. Use with nonsteroidal anti-inflammatories (indomethacin) can lead to increased risk of stomach ulcers.
  11. Use with oral hypoglycaemic agents (glibenclamide, Dimelor, glipizide) can lead to low blood sugar.
  12. Use with other salicylates can increase risk of salicylate toxicity.
  13. Use with insulin can decrease blood sugar.
  14. Use with methotrexate can increase methotrexate effect and toxicity.
  15. Use with paracetamol (paracetamol) can increase risk of kidney damage (if both are used in high doses for prolonged period).
  16. Use with alcohol or nicotine can increase risk of stomach ulcers.
  17. Use with vitamin C can decrease vitamin C effect and aspirin excretion.
  18. Use of aspirin can lead to folate depletion in the body.

USUAL DOSE

Adults: variable with trade preparation. Oral, 750-1,000 mg every 4-6 hours as needed (no more than 4 grams total per day) Delayed release preparations will be used at less frequent intervals.

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